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In vitro tests show EnerChip batteries ideal for implanted medical devices
August 2, 2012
By: DAVID SAVASTANO
Contributing Editor, Coatings World and Ink World
Cymbet Corporation announced the successful results of in vitro biocompatibility feasibility studies that were conducted to evaluate the cytotoxicity potential of the EnerChip Rechargeable Solid State Battery. EnerChip bare die battery samples were gamma sterilized and evaluated using two in vitro test methods for cytotoxicity: a) Medium Eluate Method (MEM) -1X CMEM Cell Growth Medium Extract, and b) Agar Diffusion – Solid Sample. These in vitro cell culture assays are considered to be excellent screening assays for biocompatibility. The gamma sterilized Cymbet EnerChip™ bare die batteries were found to be non-cytotoxic (0% cell lysis) using both the Medium Eluate Method Eluation Test and Agar Diffusion Test feasibility screening procedures. The lack of any adverse biological responses in these very sensitive in vitro cell culture assays is indicative (although not a guarantee) of biocompatible test results in the other in vitro and in vivo aspects of biocompatibility as suggested by the ISO 10993-1 and FDA G95-1 guidelines. Cymbet EnerChip solid state batteries are uniquely fabricated using standard semiconductor integrated circuit processes with patented construction techniques. EnerChip batteries are REACH compliant as they contain no hazardous substances as shown on the Substances of Very High Concern (SVHC) candidate list published on the European Chemicals Agency (ECHA) website. Additionally, EnerChip rechargeable solid state batteries have been fully tested as RoHS compliant. “These biocompatibility test results demonstrate why EnerChip Solid State Batteries are such a unique and safe battery technology,” said Bill Priesmeyer, Cymbet CEO. “Our medical and veterinary device customers are very pleased with the outcome of these tests. But for all our global customers, these test results highlight the intrinsic health and environmental safety characteristics of EnerChip batteries that are significantly better than legacy commercial battery chemistries.”
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